Cell Signaling Components of the Drosophila Circadian Pacemaker
نویسندگان
چکیده
of the Dissertation xi Chapter 1: Introduction 1 Chapter 2: PDF receptor preferentially couples to AC3 in small LNv cells in Drosophlia 22 Chapter 3: PDF receptor signalosome components vary between pacemaker subgroups 61 Chapter 4: Daily changes in PDF receptor signaling 83 Chapter 5: DH81 is a potent activator of the CGRP receptor encoded by CG4395 108
منابع مشابه
The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila
The neuropeptide Pigment Dispersing Factor (PDF) is essential for normal circadian function in Drosophila. It synchronizes the phases of M pacemakers, while in E pacemakers it decelerates their cycling and supports their amplitude. The PDF receptor (PDF-R) is present in both M and subsets of E cells. Activation of PDF-R stimulates cAMP increases in vitro and in M cells in vivo. The present stud...
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